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Modern Methods in Stereoselective Aldol Reactions
by Rainer Mahrwald Editor Chapter 1. Stereoselective Acetate Aldol Reactions Pedro Romea and Fèlix Urpí. Pages 1-81 Wiley, 2013 Organic Syntheses Stereoselective Synthesis of anti α-Methyl-β-Methoxy Carboxylic Compounds Pedro Romea and Fèlix Urpí. Volume 90 Pages 182-189 Organic Syntheses, 2013 e-EROS Encyclopedia of Reagents for Organic Synthesis Trichlorotitanium isopropoxide Pedro Romea and Fèlix Urpí. e-EROS, 2008 |
86. | Protected syn-Aldol Compounds from Direct, Catalytic, and Enantioselective Reactions of N‑Acyl-1,3-oxazinane-2-thiones with Aromatic Acetals | |
Mellado-Hidalgo, M.; Romero-Cavagnaro, E. A.; Nageswaran, S.; Puddu, S.; Kennignton, S. C. D.; Costa, A. M.; Romea, P.; Urpí, F.; Aullón, G.; Font-Bardia, M. | ||
Org. Lett. 2023, 25, 659-664. | ||
85. | Optimized Asymmetric Synthesis of Umuravumbolide | |
Pérez-Palau, M.; Balaguer-Garcia, E.; Romea, P.; Urpí, F. | ||
ACS Omega 2022, 7, 30835–30840. | ||
84. | Direct and Asymmetric Aldol Reactions of N-Azidoacetyl-1,3-thiazolidine-2-thione Catalyzed by Chiral Nickel(II) Complexes. A New Approach to the Synthesis of β-Hydroxy-α-Amino Acids | |
Teloxa, S. F.; Mellado-Hidalgo, M.; Kennington, S. C. D.; Romea, P.; Urpí, F.; Aullón, G.; Font-Bardia, M. | ||
Chem. Eur. J. 2022, 28, e202200671. | ||
83. | Synthesis of [(R)-DTBM-SEGPHOS]NiCl2 for the Enantioselective Acetal Formation from N-Propanoyl-1,3-Thiazinane-2-thione and Trimethyl Orthoformate | |
Kennington, S. C. D.; Romea, P.; Urpí, F. | ||
Org. Synth. 2022, 99, 1-14. | ||
82. | Stereoselective Alkylation of Chiral Titanium(IV) Enolates with tert-Butyl Peresters | |
Pérez-Palau, M.; Sanosa, N.; Romea, P.; Urpí, F.; López, R.; Gómez-Bengoa, E.; Font-Bardia, M. | ||
Org. Lett. 2021, 23, 8852-8856. | ||
81. | Synthesis and Acylation of 1,3-Thiazinane-2-thione | |
Kennington, S. C. D.; Galeote, O.; Mellado-Hidalgo, M.; Romea, P.; Urpí, F. | ||
Org. Synth. 2021, 98, 374-390. | ||
80. | Direct, Enantioselective, and Nickel(II) Catalyzed Reactions of Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes | |
Kennington, S. C. D.; Teloxa, S. F.; Mellado-Hidalgo, M.; Galeote, O.; Puddu, S.; Bellido, M.; Romea, P.; Urpí, F.; Aullón, G.; Font-Bardia, M. | ||
Angew. Chem. Int. Ed. 2021, 60, 15307-15312. | ||
79. | Direct, Enantioselective, and Nickel(II) Catalyzed Reactions of N-Azidoacetyl Thioimides with Trimethyl Orthoformate. A New Combined Methodology for the Rapid Synthesis of Lacosamide and Derivatives | |
Teloxa, S. F.; Kennington, S. C. D.; Camats, M.; Romea, P.; Urpí, F.; Aullón, G.; Font-Bardia, M. | ||
Chem. Eur. J. 2020, 26, 11540-11548. | ||
78. | Stereoselective Decarboxylative Alkylation of Titanium(IV) Enolates with Diacyl Peroxides | |
Gómez-Palomino, A.; Pérez-Palau, M.; Romea, P.; Urpí, F.; Del Olmo, M.; Hesse, T.; Fleckenstein, S.; Gómez-Benoga, E.; Sotorríos, L.; Font-Bardia, M. | ||
Org. Lett. 2020, 22, 199-203. | ||
77. | Direct anti Glycolate Aldol Reaction of Protected Chiral N‐Hydroxyacetyl Thiazolidinethiones with Acetals Catalyzed by a Nickel(II) Complex | |
Romo, J. M.; Romea, P.; Urpí, F. | ||
Eur. J. Org. Chem. 2019, 6296-6305. | ||
76. | Stereoselective Synthesis of Protected Peptides Containing an anti β-Hydroxy Tyrosine | |
Fernández-Valparis, J.; Romea, P.; Urpí, F. | ||
Eur. J. Org. Chem. 2019, 2745-2752. | ||
75. | Direct and Asymmetric Nickel(II)-Catalyzed Construction of Carbon−Carbon Bonds from N‐Acyl Thiazinanethiones | |
Kennington, S. C. D.; Taylor, A. J.; Romea, P.; Urpí, F.; Aullón, G.; Font-Bardia, M.; Ferré, L.; Rodrigalvarez, J. | ||
Org. Lett. 2019, 21, 305-309. | ||
74. | General and Stereoselective Aminoxylation of Biradical Titanium(IV) Enolates with TEMPO: a Detailed Study on the Effect of the Chiral Auxiliary | |
Kennington, S. C. D.; Gómez-Palomino, A.; Salomó, E.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Org. Biomol. Chem. 2018, 16, 4807-4815. | ||
73. | Stereoselective Oxidation of Titanium(IV) Enolates with Oxygen | |
Gómez-Palomino, A.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Synthesis 2018, 50, 2721-2726. | ||
72. | Stereoselective and Catalytic Synthesis of anti β-Alkoxy-α-Azido Carboxylic Derivatives | |
Fernández-Valparís,J.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Org. Lett. 2017, 19, 6400-6403. | ||
71. | Substrate–Controlled Michael Additions of Titanium Enolates from Chiral α-Benzyloxy Ketones to Conjugated Nitroalkenes | |
Gómez-Palomino, A.; Barrio, A.; García-Lorente, P.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Eur. J. Org. Chem. 2017, 5776-5784. | ||
70. | Experimental and Computational Evidence of the Biradical Structure and Reactivity of Titanium(IV) Enolates | |
Heras, C.; Gómez-Palomino, A.; Romea, P.; Urpí, F.; Bofill, J. M.; Moreira, I. de P. R. | ||
J. Org. Chem. 2017, 82, 8980-8916. | ||
69. | Diastereoselective and Catalytic α-Alkylation of Chiral N-Acyl Thiazolidinethiones with Stable Carbocationic Salts | |
Kennington, S. C. D.; Ferrè, M.; Romo, J. M.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
J. Org. Chem. 2017, 82, 6426-6433. | ||
68. | Total Synthesis of (+)-Herboxidiene/GEX 1A | |
Gómez-Palomino, A.; Pellicena, M.; Krämer, K.; Romea, P.; Urpí, F.; Aullón, G.; Padrón, J. M. | ||
Org. Biomol. Chem. 2017, 15, 1842-1862. | ||
67. | Substrate-controlled Aldol Reactions from Chiral α-Hydroxy Ketones | |
Aullón, G.; Romea, P.; Urpí, F. | ||
Synthesis 2017, 49, 474-503. | ||
66. | Stereoselective Synthesis of the C9–C19 Fragment of Peloruside A | |
Kennington, S.C.D.; Romo, J.M.; Romea, P.; Urpí, F. | ||
Org. Lett. 2016, 18, 3018-3021. | ||
65. | Studies towards the synthesis of tedanolide C. Construction of the C13-epi C1–C15 fragment | |
Zambrana, J.; Romea, P.; Urpí, F. | ||
Org. Biomol. Chem. 2016, 14, 5219-5223. | ||
64. | Stereoselective Alkylation of (S)-N-Acyl-4-isopropyl-1,3-thiazolidine-2-thiones Catalyzed by (Me3P)2NiCl2 | |
Fernández-Valparís, J.; Romo, J. M.; Romea, P.; Urpí, F.; Kowalski, H.; Font-Bardia, M. | ||
Org. Lett. 2015, 17, 3540-3543. | ||
63. | Kinetic resolution of esters from secondary and tertiary benzylic propargylic alcohols by an improved esterase-variant from Bacillus sp. BP-7 | |
Fillat, A.; Romea, P.; Pastor, F. I. J.; Urpí, F.; Díaz, P. | ||
Catalysis Today 2015, 255, 16-20. | ||
62. | Stereoselective Acetate Aldol Reactions of α-Silyloxy Ketones | |
Lorente, A.; Pellicena, M.; Romea, P.; Urpí, F. | ||
Tetrahedron 2015, 71, 1023-1035. | ||
61. | Substrate-Controlled Michael Additions of Chiral Ketones to Enones | |
Fàbregas, M.; Gómez-Palomino, A.; Pellicena, M.; Reina, D. F.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Org. Lett. 2014, 16, 6220-6223. | ||
60. | Stereoselective Aminoxylation of Biradical Titanium Enolates with TEMPO | |
Gómez-Palomino, A.; Pellicena, M.; Romo, J. M.; Solà, R.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Chem. Eur. J. 2014, 20, 10153-10159. | ||
59. | Stereoselective Titanium-Mediated Aldol Reactions of a Chiral Lactate-Derived Ethyl Ketone with Ketones | |
Alcoberro, S.; Gómez-Palomino, A.; Solà, R.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Org. Lett. 2014, 16, 584-587. | ||
58. | Improving enantioselectivity towards tertiary alcohols using mutants of Bacillus sp. BP-7 esterase EstBP7 holding a rare GGG(X)-oxyanion hole | |
Fillat, A.; Romea, P.; Urpí, F.; Pastor, F. I. J.; Diaz, P. | ||
Appl. Microbiol. Biotechnol. 2014, 98, 4479-4490. | ||
57. | Diastereoselective Methyl Orthoformate Alkylations of Chiral N-Acyl Thiazolidinethiones Catalyzed by Nickel(II) Complexes | |
Gálvez, E.; Romo, J. M.; Nubiola, I.; Romea, P.; Urpí, F.; Kindred, M. | ||
Adv. Synth. Catal. 2013, 355, 2781-2786. | ||
56. | Stereoselective titanium-mediated aldol reactions from a chiral isopropyl ketone | |
Zambrana, J.; Romea, P.; Urpí, F. | ||
Chem. Commun. 2013, 49, 4507-4509. | ||
55. | Stereoselective synthesis of C-glycosides by addition of titanium enolates from a chiral N-glycolyl thiazolidinethione to glycals | |
Gálvez, E.; Sau, M.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Tetrahedron Lett. 2013, 54, 1467-1470. | ||
54. | Stereoselective titanium-mediated aldol reactions of α-benzyloxy methyl ketones | |
Pellicena, M.; Solsona, J. G.; Romea, P.; Urpí, F. | ||
Tetrahedron 2012, 68, 10338-10350. | ||
53. | Diastereoselective Additions of Titanium Enolates from N-Glycolyl Thiazolidinethiones to Acetals | |
Baiget, J.; Caba, M.; Gálvez, E.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
J. Org. Chem. 2012, 77, 8809-8814. | ||
52. | Stereoselective Synthesis of protected 3-amino-3,6-dideoxyaminosugars | |
Nebot, J.; Romea, P.; Urpí, F. | ||
Org. Biomol. Chem. 2012, 10, 6395-6403. | ||
51. | Total Synthesis of (+)-Herboxidiene from Two Chiral Lactate-derived Ketones | |
Pellicena, M.; Krämer, K.; Romea, P.; Urpí, F. | ||
Org. Lett. 2011, 13, 5350-5353. | ||
50. | Highly Stereoselective Titanium-mediated Aldol Reaction from (S) 4-Benzyloxy-3-methyl-2-butanone | |
Zambrana, J.; Romea, P.; Urpí, F.; Luján, C. | ||
J. Org. Chem. 2011, 76, 8575-8587. | ||
49. | Highly stereoselective titanium-mediated aldol reactions from chiral α-silyloxy ketones. A reliable tool for the synthesis of natural products | |
Esteve, J.; Jiménez, C.; Nebot, J.; Velasco, J.; Romea, P.; Urpí, F. | ||
Tetrahedron 2011, 67, 6045-6056. | ||
48. | Stereoselective Acetate Aldol Reactions from Metal Enolates | |
Ariza, X.; Garcia, J.; Romea, P.; Urpí, F. | ||
Synthesis 2011, 2175-2191. | ||
47. | Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives | |
Esteve, J.; Lorente, A.; Romea, P.; Urpí, F.; Ríos-Luci,C.; Padrón, J. M. | ||
Eur. J. Org. Chem. 2011, 960-967. | ||
46. | Highly Stereoselective Synthesis of syn-1,3-Diols through a Sequential Titanium-Mediated Aldol Reaction and LiBH4 Reduction | |
Esteve, J.; Matas, S.; Pellicena, M.; Velasco, J.; Romea, P.; Urpí, F.; Font-Bardia, M. | ||
Eur. J. Org. Chem. 2010, 3146-3151. | ||
45. | 1,4-syn-Asymmetric induction in the titanium-mediated aldol reactions of chiral methyl α-silyloxy ketones | |
Lorente, A.; Pellicena, M.; Romea, P.; Urpí, F. | ||
Tetrahedron Lett. 2010, 51, 942-945. | ||
44. | Stereoselective Synthesis of α- and β-C-Glycosides by Addition of Titanium Enolates to Glycals | |
Gálvez, E.; Larrosa, I.; Romea, P.; Urpí, F. | ||
Synlett 2009, 2982-2986. | ||
43. | Stereoselective Synthesis of Highly Functionalized Structures from Lactate-Derived Halo Ketones | |
Nebot, J.; Romea, P.; Urpí, F. | ||
J. Org. Chem. 2009, 74, 7518-7521. | ||
42. | New Approach to the Stereoselective Synthesis of Tertiary Methyl Ethers | |
Checa, B.; Gálvez, E.; Parelló, R.; Sau, M.; Romea, P.; Urpí, F.; Font-Bardia, M.; Solans, X. | ||
Org. Lett. 2009, 11, 2193-2196. | ||
41. | Stereoselective Synthesis of anti α-Methyl-β-methoxy Carboxylic Compounds | |
Gálvez, E.; Romea, P.; Urpí, F. | ||
Org. Synth. 2009, 86, 81-91. | ||
40. | Preparation of (S)-4-Isopropyl-N-propanoyl-1,3-thiazolidine-2-thione | |
Gálvez, E.; Romea, P.; Urpí, F. | ||
Org. Synth. 2009, 86, 70-80. | ||
39. | Stereoselective addition of titanium enolates to functionalized acetals. A novel approach to the γ-amino acids of bistramides and FR252921 | |
Gálvez, E.; Parelló, R.; Romea, P.; Urpí, F. | ||
Synlett 2008, 2951-2954. | ||
38. | 1,4-Asymmetric induction in the titanium-mediated aldol reactions of α-benzyloxy methyl ketones | |
Pellicena, M.; Solsona, J. G.; Romea, P.; Urpí, F. | ||
Tetrahedron Lett. 2008, 49, 5265-5267. | ||
37. | On the influence of chiral auxiliaries in the stereoselective cross-coupling reactions of titanium enolates and acetals | |
Baiget, J.; Cosp, A.; Gálvez, E.; Gómez-Pinal, L ; Romea, P.; Urpí, F. | ||
Tetrahedron 2008, 64, 5637-5644. | ||
36. | Unconventional Biradical Character of Titanium Enolates | |
Moreira, I. de P. R.; Bofill, J. M.; Anglada, J. M.; Solsona, J. G.; Nebot, J.; Romea, P.; Urpí, F. | ||
J. Am. Chem. Soc. 2008, 130, 3242-3243. | ||
35. | Synthesis of six-membered oxygenated heterocycles through carbon-oxygen bond-forming reactions | |
Larrosa, I.; Romea, P.; Urpí, F. | ||
Tetrahedron 2008, 64, 2683-2723. | ||
34. | Highly Stereoselective TiCl4-Mediated Aldol Reactions from (S)-2-Benzyloxy-3-pentanone | |
Rodríguez-Cisterna, V.; Villar, C.; Romea, P.; Urpí, F. | ||
J. Org. Chem. 2007, 72, 6631-6633. | ||
33. | Stereoselective titanium-mediated aldol reaction of (S)-2-tert-butyldimethylsilyloxy-3-pentanone | |
Nebot, J.; Figueras, S.; Romea, P.; Urpí, F.; Ji, Y. | ||
Tetrahedron 2006, 62, 11090-11099. | ||
32. | Synthesis of the C9-C21 fragment of debromaplysiatoxin and oscillatoxins A and D | |
Cosp, A.; Llàcer, E.; Romea, P.; Urpí, F. | ||
Tetrahedron. Lett. 2006, 47, 5819-5823. | ||
31. | Studies on the hydrogenolysis of benzyl ethers | |
Llàcer, E.; Romea, P.; Urpí, F. | ||
Tetrahedron. Lett. 2006, 47, 5815-5818. | ||
30. | Stereoselective Synthesis of the Western Hemisphere of Salinomycin | |
Larrosa, I.; Romea, P.; Urpí, F. | ||
Org. Lett. 2006, 8, 527-530. | ||
29. | Highly stereoselective aldol reaction based on titanium enolates from (S)-1-benzyloxy-2-methyl-3-pentanone | |
Solsona, J. G.; Nebot, J.; Romea, P.; Urpí, F. | ||
J. Org. Chem. 2005, 70, 6533-6536. | ||
28. | A stereoselective aldol-reduction approach to polyoxygenated natural products. Synthesis of C1-C6 fragment of erythronolides | |
Galobardes, M.; Gascón, M.; Romea, P.; Urpí, F. | ||
Lett. Org. Chem. 2005, 2, 312-315. | ||
27. | Double Stereodifferentiating Aldol Reactions Based on Chiral Ketones Derived from Lactic Acid: Synthesis of C1-C6 Fragment of Erythronolides | |
Solsona, J. G.; Nebot, J.; Romea, P.; Urpí, F. | ||
Synlett 2004, 2127-2130. | ||
26. | Stereoselective titanium-mediated syn-aldol reaction from a lactate-derived chiral ethyl ketone | |
Solsona, J. G.; Romea, P.; Urpí, F. | ||
Tetrahedron Lett. 2004, 45, 5379-5382. | ||
25. | Studies Directed toward the Construction of Polypropionate Fragment of Superstolide A | |
Solsona, J. G.; Romea, P.; Urpí, F. | ||
Org. Lett. 2003, 5, 4681-4684. | ||
24. | Studies on the Intramolecular CH···X (X= O, S) Interactions in (S)-N-Acyl-4-isopropyl-1,3-thiazolidine-2-thiones and Related 1,3-Oxazolidin-2-ones | |
Cosp, A.; Larrosa, I.; Anglada, J. M.; Bofill, J. M.; Romea, P.; Urpí, F. | ||
Org. Lett. 2003, 5, 2809-2812. | ||
23. | Synthesis of O-Benzyl Protected anti Aldols through the Cross-Coupling Reaction of Dibenzyl Acetal with a Chiral Titanium Enolate | |
Cosp, A.; Larrosa, I.; Vilasís, I.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Synlett 2003, 1109-1112. | ||
22. | Highly Stereoselective Aldol Reaction of Titanium Enolates from Lactate-Derived Chiral Ketones | |
Solsona, J. G.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Org. Lett. 2003, 5, 519-522. | ||
21. | Unprecedented Highly Stereoselective α- and β-C-Glycosidation with Chiral Titanium Enolates | |
Larrosa, I.; Romea, P.; Urpí, F.; Balsells, D.; Vilarrasa, J.; Font-Bardia, M.; Solans, X. | ||
Org. Lett. 2002, 4, 4651-4654. | ||
20. | Stereoselective synthesis of syn,syn-2-methyl-1,3-diols through one pot aldol-reduction sequence | |
Galobardes, M.; Mena, M.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 2002, 43, 6145-6148. | ||
19. | β3-Amino acids by nucleophilic ring-opening of N-nosyl aziridines | |
Farràs, J.; Ginesta, X.; Sutton, P.; Taltavull, J.; Egeler, F.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron 2001, 57, 7665-7674. | ||
18. | Enantiopure β-methoxy carboxyl derivatives from a chiral titanium enolate and dimethyl acetals | |
Cosp, A.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 2001, 42, 4629-4631. | ||
17. | Enantioselective Addition of a Chiral Thiazolidinethione-Derived Titanium Enolate to Acetals | |
Cosp, A.; Romea, P.; Talavera, P.; Urpí, F.; Vilarrasa, J.; Font-Bardia, M.; Solans, X. | ||
Org. Lett. 2001, 3, 615-617. | ||
16. | Simple and Efficient Preparation of Enantiopure Alkyl α-Hydroxyalkyl Ketones | |
Ferreró, M.; Galobardes, M.; Martín, R.; Montes, T.; Romea, P.; Rovira, R.; Urpí, F.; Vilarrasa, J. | ||
Synthesis 2000, 1608-1614. | ||
15. | Pseudoaxially Disubstituted Cyclo-β3-tetrapeptide Scaffolds | |
Sutton, P. W.; Bradley, A.; Farràs, J.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron 2000, 56, 7947-7958. | ||
14. | Enolization of Chiral α-Silyloxy Ketones with Dicyclohexylchloroborane. Application to Stereoselective Aldol Reactions | |
Galobardes, M.; Gascón, M.; Mena, M.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Org. Lett. 2000, 2, 2599-2602. | ||
13. | Reaction of Chiral Titanium Z-Enolates with Chiral α-Silyloxy Aldehydes. Syntheses of NFX-2 and Antimycinone | |
Esteve, C.; Ferreró, M.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1999, 40, 5083-5086. | ||
12. | Reaction of Achiral Titanium Z-Enolates with Chiral α-Silyloxy Aldehydes | |
Esteve, C.; Ferreró, M.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1999, 40, 5079-5082. | ||
11. | Design and synthesis of a novel cyclo-β-tetrapeptide | |
Sutton, P. W.; Bradley, A.; Elsegood, M. R. J.; Farràs, J.; Jackson, R. F. W.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1999, 40, 2629-2632. | ||
10. | Syntheses of the C-1 alkyl side chains of Zaragozic acids A and C | |
Bach, J.; Galobardes, M.; García, J.; Romea, P.; Tey, C.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1998, 39, 6765-6768. | ||
9. | Simple and Efficient Preparation of Ketones from Morpholine Amides | |
Martín, R.; Romea, P.; Tey, C.; Urpí, F.; Vilarrasa, J. | ||
Synlett 1997, 1414-1416. | ||
8. | Highly Stereoselective Aldol Reactions of Titanium Enolates from Ethyl α-Silyloxyalkyl Ketones | |
Figueras, S.; Martín, R.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1997, 38, 1637-1640. | ||
7. | A Simple Procedure for the Preparation of Enantiopure Ethyl α-Hydroxyalkyl Ketones | |
Martín, R.; Pascual, O.; Romea, P.; Rovira, R.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1997, 38, 1633-1636. | ||
6. | Studies in Macrolide Synthesis: A Stereocontrolled Synthesis of Oleandolide Employing Reagent- and Substrate-Controlled Aldol Reactions of (S)-1-(Benzyloxy)-2-methylpentan-3-one | |
Paterson, I.; Norcross, R. D.; Ward, R. A.; Romea, P.; Lister, M. A. | ||
J. Am. Chem. Soc. 1994, 116, 11287-11314. | ||
5. | Substrate-Controlled Aldol Reactions of Chiral Ethyl Ketones; Application to the Total Synthesis of Oleandomycin | |
Paterson, I.; Ward, R. A.; Romea, P.; Norcross, R. D. | ||
J. Am. Chem. Soc. 1994, 116, 3623-3624. | ||
4. | Alternative Procedures for the Macrolactamisation of ω-Azido Acids | |
Bosch, I.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron Lett. 1993, 34, 4671-4674. | ||
3. | Improved Methods for the N-Nitration of Amides | |
Romea, P.; Aragonès, M.; García, J.; Vilarrasa, J. | ||
J. Org. Chem. 1991, 56, 7038-7042. | ||
2. | A Fast Procedure for the Reduction of Azides and Nitro Compounds Based on the Reducing Ability of Sn(SR)3- Species | |
Bartra, M.; Romea, P.; Urpí, F.; Vilarrasa, J. | ||
Tetrahedron 1990, 46, 587-594. | ||
1. | Nitrosation of Hindered Amides | |
Romea, P.; Urpí, F.; Vilarrasa, J. | ||
J. Org. Chem. 1989, 54, 3209-3211. |